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Job description: The International Research Center for Medical Sciences (IRCMS) was established in 2015 as the center of excellence in Kumamoto University for world-class research in life sciences through the internationalization of its research environment and the establishment of global collaborations. The Center features an open lab layout with few walls and partitions between labs to facilitate communication among scientists. English is the official language for all seminars and lab meetings to promote international scientific discourse. The laboratory of Proteostasis in Stem Cell was newly establshed in 2021. We conduct research in hematology (especially hematopoietic stem cell biology and erythropoiesis) and fetal development. In this particular project, the successful candidate is expected to actively conduct our ongoing projects investigating roles of maternal environment in fetal organ formation. The lab is a part of International Research Center for Medical Sciences (IRCMS), so that the researcher will have a full access to our core facility and common research activities.

Available positions: Postdoctoral fellow (1-2 positions), up to 3 years. The successful candidate is expected to start as soon as possible.

Address of work location: International Research Center for Medical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto City 860-0811, Japan

Treatment after recruitment: Compensation will be decided according to an assessment of the candidate based on her/his experiences and scientific achievements as well as Kumamoto University's regulation.

Qualifications needed for this position: Applicants need to hold Ph.D degree (when starting). It is desired to have experiences working in the life science field, holding skills to handle animal models (mice), and sufficient communication skills in English.
Following experiences could be advantages: having studied in hematology field; skills to use flow cytometers; skills to perform histological analyses.

Application documents: Interested applicants are encouraged to assemble following documents and submit as an application packet to kenmiharada(at)kumamoto-u.ac.jp

1. Letter of intent

2. Curriculum vitae with e-mail address, photo and contact information

3. A brief description of candidate's previous research

4. A statement of research accomplishment

5. A list of publication

6. Contact information of 2 references

Selection details: Upon paper selection, top applicants will be invited for an interview (via Skype or Zoom) and the final result will be noticed via e-mail address.

Contact information:
Kenichi Miharada, Ph.D.
Professor , Lab of Proteostasis in Stem Cell
International Research Center for Medical Sciences, Kumamoto University
2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan
E-mail: kenmiharada(at)kumamoto-u.ac.jp
Tel/Fax: +81-96-373-6885

2022-01-20 2022-04-20

About the position
The Department of Animal and Aquacultural Sciences, Faculty of Biosciences at the Norwegian University of Life Sciences (NMBU) has a vacant 2 year postdoctoral position in functional genomics. The position is financed with the RCN-funded project SalmoSV. The goal of this project is to reveal the functional impact of target structural variants on early development in Atlantic salmon using CRISPR-Cas9 and/or Tol2 transgenesis in embryo and/or cell lines. To achieve this goal, the recruited researcher/postdoc will collaborate with the ongoing Atlantic salmon genomics project team at CIGENE.

The candidate will:

  • Participate in the selection process of targets from the candidate list
  • design, develop and perform CRISPR experiments and Tol2 transgenesis of salmon embryos and/or cell lines
  • investigate phenotype in Atlantic salmon embryo, skin and liver cell lines
  • Illumina-based DNA, RNA sequencing in collaboration with bioinformatics researchers
  • disseminate research in leading scientific journals in the field
  • Work with other researchers, including PhD and master’s students

Competence
The applicant must document expertise and interest in the research subject.
Required Academic qualifications

  • PhD degree in genetics, molecular biology or related field
  • Experience with gene-editing and molecular biology

The following experiences and skills will be preferred:

  • Experience with construction of vectors, CRISPR in animals, cell cultures and imaging

Remuneration
The position is placed in government pay scale position code 1352 Postdoctoral Fellow, wage framework 24 (salary grade 59-77) (NOK 523.200-741.300), on the Norwegian Government salary scale upon employment depending on qualifications.

Application and submit (click here)

  1. A letter of intent includes:
    1. Why are you interested in this particular project?
    2. How can you contribute to the project based on your specific skillsets including gene editing?
  2. Curriculum vitae + publication list + at least two academic reference persons.

For further information, please contact Dr. Marie Saitou (about project overview) and Dr. Guro Katrine Sandvik (about technical detail) Lab Website, information to applicants

2022-01-13 2022-04-13

Job Description
We are soliciting applications for a Postdoctoral Researcher who will work on the KAKENHI project, Grant-in-Aid for Transformative Research Areas (A) "Development of Molecular Memory/Molecular Learning Circuits for Minimal Artificial Brain (FY2020-2024, Co-Investigator: Ken Komiya)" in the project area of "Molecular Cybernetics," and JST-RISTEX RInCA program "Development of an RRI Practice Model for Molecular Robotics Premised on Researchers Autonomy (FY2021-2024, PI: Ken Komiya)". The successful applicant will engage in the following research and development plans.

[Research Description]
The SUGAR Program of X-star in JAMSTEC conducts research to explore microorganisms in extreme environments and create artificial life functions by elucidating the functions of these microorganisms. As part of this effort, we are developing biomolecular systems that express advanced functions beyond living organisms.

We invite applicants for the position of Postdoctoral Researcher who will work in life science research, including the creation of artificial cells and elucidation of the origin of life. In our project, a synthetic approach is encouraged, such as integrating reactions of biomolecules and enzymes to realize highly sensitive molecular detection and precise molecular manipulation, or the construction of functional molecular systems that can perform efficient information processing and molecular production in a manner similar to living organisms. The successful applicant will be expected to engage in the following works through active collaboration with researchers in JAMSTEC and other domestic and foreign institutes. The research target and approach will be flexibly determined by taking into account the applicant’s area of expertise and experience.

1) Construction of molecular circuits using DNA and enzymes, and their application to the measurement and control of cellular processes.

2) In vitro construction of artificial metabolic systems to investigate biological functions and produce useful molecules

3) Presenting the results of the research and development at academic conferences, publishing them as peer-reviewed papers, and implementing these advances in society.

[Relevant Research Fields]
Biomolecular Chemistry, Synthetic Biology, Microbiology, Bioinformatics, Evolutionary Molecular Engineering, µ-TAS, DNA Nanotechnology

Requirements
Applicants are required to have been awarded or expect to have obtained a Ph.D. in a related field by the effective date of employment. In addition, no more than 5 years can have passed between the last day of the fiscal year in which the applicants obtained a Ph.D. and the effective date of employment. (i.e., applicants who earned a Ph.D. after April 2016 are eligible.)

Work Place
Japan Agency for Marine-Earth Science and Technology (JAMSTEC)
Yokosuka Headquarters, 2-15 Natsushima-cho, Yokosuka city, Kanagawa, 237-0061, JAPAN
*Measures to prevent passive smoking: No smoking on the premises (smoking areas are available outside), no work in areas where smoking allowed.

Working Conditions & Contract Period
(1) Number of positions:
1 position for a Postdoctoral Researcher

(2) Type of contract:
Fixed-term employee

(3) Working Hours:
Discretionary labor system

(4) Contract Period:
Total period will be terminated on March 31, 2025 after two contract renewals.
*First contract period is from April 1, 2022 to March 31, 2023.
*Effective date of employment is negotiable. However it might be changed due to the influence of COVID-19 expansion.
*Contract period can be renewed depending on the performance and working attitude of the successful applicant. *Contract period might change due to budget constraints of the projects.
*In accordance with JAMSTEC bylaws, on reaching the age of 65 during an employed fiscal year, the contract period will expire at the end of the same fiscal year. This bylaw may change.
*This position is a non-tenure-track, fixed-term employee position.

Salary
Annual salary (paid in 1/12 equal monthly payments)
JPY 5,250,000

*There is no raise.
*Bonus and retirement allowance are included in the annual salary.

Closing Date
January 21, 2022 at 13:00 in Japan time (The application documents must arrive at JAMSTEC by this date.)

Contact (application documents must be sent to this address)
Human Resources Section, Human Resources Dept., JAMSTEC
TEL: +81-45-778-5811
(Email: recruit-app[at]jamstec.go.jp)
*Please replace [at] with @ when addressing Emails.
*For inquiries by Email, please include "SUGAR EGP21-008" in the subject line.

For further information, please visit
http://www.jamstec.go.jp/e/work_with_us/jobs/details/sugar20220121.html

2021-12-24 2022-01-21

Medical Research Institute (MRI) of Tokyo Medical and Dental University (TMDU) invites applications for a faculty position (Assistant Professor)) in the field of Medical Chemistry.

1. Position
Assistant Professor

2. Areas of Research
Our goal is to define the molecular basis for the mechanism of organ formation, regeneration, and maintenance using knockout mice and mutant fish. To accomplish this goal, we have focused on defining signaling molecules and pathways that regulate liver and brain formation and maintenance. Our study will provide new insights into understanding the precise molecular mechanisms that underlie organ failures found in human diseases and will lead to the development of new rational therapy for the diseases. In this recruitment, we seek a researcher who has a passion to clarify these mechanisms with a strong background in cell biology using mice and human iPS cells.

3. Terms and Conditions of Employment
Full-time position with a contract, which will start April 1, 2022, not exceeding third years period. Renewable based on evaluation according to the rules and regulations of TMDU, but not exceeding March 31, 2027. No further renewal possible.
Salary will be determined by the annual salary system outlined by TMDU regulations.

Female applicants are strongly encouraged to apply for this position, as TMDU promotes gender-equality work environment. We provide career support programs for all staff that enable them to balance work and life, such as childbirth and child rearing.

4. Application Forms

(1)  Resume (Curriculum Vitae, etc.) (free form).

(2)  List of publications (free form).

(3)  Reprints of representative publications (up to 3 papers, photocopies acceptable).

(4)  Summary of the representative publications (100 words each).

(5)  List of research grants and patents (free form).

(6)  Summary of previous research contributions and future research and education plans (in 500 words).

(7)  A list of other achievements (Awards etc).

5. Deadline
February 1, 2022, Japan Standard Time.

6. Inquiry
Administration Office, Medical Research Institute, Tokyo Medical and Dental University
E-Mail: pr.mri.adm[at]tmd.ac.jp *Please replace [at] with @ when addressing Emails
Tel: +81-3-5803-4504

7. How to Apply
All the application documents must be sent to Administration Office. To apply, please enter the following [E-mail contents] at pr.mri.adm[at]tmd.ac.jp *Please replace [at] with @ when addressing Emails
Please contact us by E-mail by January 31, 2022 (Monday).
We will send the URL and manual for submission to the university to the "destination email address".
[E-mail contents]

• Subject: "Application for the Assistant Professor position in the Developmental and Regenerative Biology"

• Full name

• Destination email address

All information will be treated with the strictest confidentiality in accordance with pertinent laws and rules.

2021-11-22 2022-01-31

Open positions
Team Leader: A few position

Qualifications
A holder of Ph.D. or equivalent degree.

Work location
RIKEN Center for Biosystems Dynamics Research (Kobe Campus-East-West)
2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan

Research field
The RIKEN Center for Biosystems Dynamics Research (BDR) aims to understand the general principles of organismal temporal dynamics throughout the lifespan from birth to death, including aging. Our interdisciplinary approaches include imaging, multi-omics, theory, molecular biology, stem cell biology, organoids, and diverse animal models.
We are now seeking to recruit Team Leaders who conduct challenging and innovative research to pioneer new fields of life cycle science. How organisms including humans control the transitions of life stages, and how they achieve long-term control across distinct life stages, are our keen interests. Topics include metabolic, epigenetic, and morphogenetic transitions in the life cycle, multi-organ interactions, stem cell-based tissue maintenance, transgenerational interactions (e.g. mother-to-fetal communication), aging, and any other topics that will potentially lead to conceptual advances in life cycle science. We encourage proposals using unprecedented interdisciplinary approaches, such as combinations of reconstructing organs, comparing diverse animal models and primates including human subjects, linking events at multiple scales from molecules and cells to tissues and organs, and taking advantage of any other cutting-edge technologies.
BDR provides early-career Team Leaders with an excellent environment for their independent research, including internationally competitive start-up packages and annual research funds as well as mentoring by experienced senior PIs. The Team Leader will have access to cutting-edge facilities including for various animal models, mouse genome engineering, multi-scale imaging and omics, and structural biology, and have opportunities for active collaborations with medical institutions, industry, and affiliated graduate schools. For more information, please visit the BDR website.
https://www.bdr.riken.jp/en/index.html
We welcome applications from candidates of any gender or nationality, and encourage applications from those who will broaden RIKEN's diversity. The working language for all discussions open to BDR members is English.

Deadline
Applications must arrive no later than noon, February 28, 2022 (Japan Standard Time)

Start of employment
Negotiable (After October 1, 2022)

Details
For more information and required application documents, please visit the application website:
https://www.riken.jp/en/careers/researchers/20211101_1/index.html

2021-11-05 2022-02-28

Open positions
Laboratory Head: 1 position (full professor level)

Qualification
Applicants must have an outstanding research record and the ability to lead the above research field internationally. We welcome applicants of all nationalities.

Work location
Branch and address
RIKEN Yokohama Campus (1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045)

Research field and overview
RIKEN's research is based on synthesis and interdisciplinarity, and with free thinking as its basic philosophy, RIKEN promotes research that goes beyond the boundaries of conventional research fields, while at the same time responding to the needs of society from a strategic perspective.

RIKEN invites applications for the position of Laboratory Head (indefinite-term employment position) to serve in a leadership position in the following research area. The successful candidate will be responsible for directing research projects from a medium-to-long-term perspective.

Field: Non-coding RNA biology
Non-coding RNAs (ncRNAs) are often correlated with human diseases and also contribute to various biological phenomenon. However, the mechanisms of how ncRNAs function and how their expression is regulated remain unknown. From a translational perspective, expansion of ncRNA research is expected to contribute to nucleic acids therapeutics. RIKEN seeks a principal investigator who will lead a laboratory with a focus on elucidating ncRNA functions in biology and in human diseases. The successful candidate is expected to conduct cutting edge researches in ncRNA biology with experimental approaches, such as biochemistry, cell biology and genetics, and/or with data-driven approaches, such as structural biology, genomics and large-scale data-sciences.

RIKEN Center for Integrative Medical Sciences (IMS) provides the laboratory head with a starting-up package including research fund and a supportive environment for conducting independent research.

For an overview of RIKEN IMS, please visit the IMS website.
https://www.ims.riken.jp/english/

Deadline
The application must arrive no later than noon, January 11, 2022 (Japan Standard Time)

Start of Employment
RIKEN expects that the successful candidate will be able to take up this position at the earliest opportunity on or after October 1, 2022.

Details
For more information and required application documents, please visit the application website:
https://www.riken.jp/en/careers/researchers/20211008_1/index.html

2021-10-12 2022-01-11

Open positions
Principal Investigator: 1 position (tenured full professor level)

Qualifications
Applicants must have an outstanding research record and the ability to lead the above research field internationally. We welcome applicants of all nationalities.

Work location
RIKEN Yokohama Campus (1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045)

Research field and overview
RIKEN's research is based on synthesis and interdisciplinarity. With, free-thinking as its basic philosophy, RIKEN promotes research that goes beyond the boundaries of conventional research fields, while at the same time responding to the needs of society from a strategic perspective.

RIKEN invites applications for the position of Principal Investigator (PI, indefinite-term employment position) to serve in a leadership position in the following research area. The successful candidate will be responsible for directing research projects from a mid-to-long-term perspective.

Field: in situ Structural Biology
RIKEN has introduced cryo-electron microscopes (Tecnai Arctica, Krios G4) and cryo-FIB/SEM (Aquilos2) to establish the research infrastructure for single particle analysis and cryo-electron tomography. In this call for applications, we are looking for a PIwho will play a central role in promoting research on "in situ structural biology," i.e., "in situ analysis of complex structures of biological macromolecules functioning in cells," by making full use of these research facilities, especially cryo-EMs.
Since this field is still in its infancy, we welcome not only candidates with experience and achievements in cryo-EM tomography, but also ambitious candidates who will pioneer the field of in situ structural biology research based on their past research experiences, such as single-particle analysis of reconstituted functional complexes in vitro. We are looking for a candidate who is willing to explore the field of in situ structural biology based on his or her previous research experience.
The Center for Biosystems Dynamics Research (BDR) aims to understand the general principles of organismal temporal dynamics throughout the lifespan from birth to death, including aging. We have more than 70 laboratories working on various approaches including imaging, multi-omics, theoretical biology, molecular biology, structural biology, stem cell biology, organoids, and various animal models. Each PI will be provided with a research environment including start-up and research funding for independent research. In addition, PIs are encouraged to carry out research projects in collaboration with other laboratories to achieve the Center's goals, for which additional funding will be provided. The laboratory head may employ researchers, technicians, and assistants with these research funds and any external funding obtained. Support is provided for the maintenance and management of laboratory animals, genetically modified animal production, optical imaging, electron microscopy (TEM, SEM), and omics analysis. The Center also provides opportunities for joint research through its network of medical institutions and companies and can accept graduate students through its affiliated graduate school system. For more information, please visit the BDR website (https://www.bdr.riken.jp/en/index.html).
We are looking for a person who will lead the next generation of structural biology at the Center and RIKEN, and who will be a core member of the international leadership in this research field. Since the above facilities are part of the project to promote the sharing of advanced research facilities, this laboratory is also expected to actively contribute to the shared service of cryo-electron microscopy.

 

Deadline
The application must arrive no later than noon, January 7, 2022 (Japan Standard Time)

Start of employment
October 1, 2022 or earliest possible date after this date.

Details
For more information and required application documents, please visit the application website:
https://www.riken.jp/en/careers/researchers/20211008_2/index.html

2021-10-12 2022-01-07

Description:
The He lab at UC-Berkeley is one of the pioneers in studying the functions of the non-coding genome in mammalian development and disease. We employ novel approaches in mouse genetics, comparative genomics, cell and molecular biology to understand the functional importance and the molecular regulation of various non-coding elements, including microRNAs (miRNAs), long ncRNAs and more recently, transposon elements. Combining new technology of mouse CRISPR genome engineering and innovative live cell imaging technologies, the He lab pioneers in vivo studies to elucidate the new cellular functions and new molecular mechanisms of ncRNAs and transposons, which often lead to exciting new directions in the field. The discoveries of the He lab have been well recognized by prestigious journals including Nature, Science and Cell.

The PI, Dr. Lin He, was awarded the prestigious MacArthur Fellowship and the Searle Scholar in 2009, and is currently a Howard Hughes Medical Institute (HHMI) Faculty Scholar, and a Thomas and Stacey Siebel distinguished chair professor at UC-Berkeley. More information about The He Lab can be found via http://helabucb.weebly.com/

The He lab is in the MCB department at UC-Berkeley, which encompasses a breadth of disciplines spanning all levels of organization and encompassing diverse organisms. UC-Berkeley is at a central location in the San Francisco bay area, surrounded by many excellent academic institutions and biotech/pharmaceutical companies. The breath of training, combined with the unique location of Berkeley in the center of biomedical research, offer a nurturing environment for the next-generation scientist to launch on a successful career in biomedical research in academia and industry.

Responsibilities:
The He Lab at UC-Berkeley is seeking a creative, accomplished, and highly motivated postdoctoral scholars to work within our graduate students and postdoctoral fellows. The postdoctoral fellow will work closely with the PI and junior students/staff members to study the roles of non-coding elements in mammalian preimplantation development, embryonic stem cell biology, cilia biology and disease, and lung cancer metastasis. The postdoc fellow will have a unique opportunity to learn our novel in vivo CRISPR-genome editing tools, and to create a innovative research program using in vivo biology.

Minimum/Basic Qualifications Required (At the time of application):
Ph.D. in Genetics, Genomics, Cell Biology, Molecular Biology, Biochemistry, Bioengineering, or related field, with a track record of first-author publication(s) in peer-reviewed journals. Successful trainees are those who are truly excited about science, who often have prior experiences in mouse genetics, RNA biology, imaging, or genomics. Excellent writing and communication skills in English is preferred.

To Apply:
Interested individuals should submit an updated CV, and contact information for 3 recommendation letters, and a cover letter. (Letters of reference may be requested of the finalists). Please send these documents to Dr. Lin He at glinhe[at]gmail.com (*Please replace [at] with @ when addressing Emails)

2021-10-05 2022-01-05